Tag: "Gene-Knockout-Techniques"

Generation of -Knockout Human Embryonic Stem Cell Lines to Model Autophagic Dysfunction and Exosome Secretion in Fabry Disease-Associated Hypertrophic Cardiomyopathy.

Cells

Monday 08 April 2019
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metabolismhumansanimalsgeneticsexosomescytologymiceinduced pluripotent stem cellsphysiologydrug effectsembryonic stem cellscell differentiationcell linepathologyculturedfemalecellscell proliferationmalemicrornasgene expression regulationmethodsmesenchymal stem cellschemistrycell movementfibroblastsimmunologyratstumoranimaltransplantationbiomarkersdisease modelspharmacologytherapycell communicationinbred c57blmyocytescardiacextracellular vesiclesneuronsapoptosisbloodculture mediarnaconditionedembryoadministration dosagehuman embryonic stem cellsmyocardiumneoplasmsagedbraincell survivalcellular reprogrammingdnabinding proteinsmammalianmelanomamicroscopymodelsneural stem cellssignal transductionstem cell transplantationbiologicaldeficiencyendothelial cellsmutationpluripotent stem cellsregenerationadultalzheimer diseasecell culture techniquescellular senescencecytokinesdevelopmentaldrug delivery systemsenzymologyfibrosisgenetichek293 cellsimmunohistochemistrymouse embryonic stem cellsmuscleregenerative medicineastrocytesbioengineeringbiosynthesisblottingcell and tissuebased therapycellderived microparticlescoculture techniquesdownregulationepigenesishearthuman umbilical vein endothelial cellslungmyocardial infarctionneoplasticneovascularizationskeletal